IgE class switch recombination is regulated by CaMKII via NF-ΚB alternative pathway
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چکیده
منابع مشابه
IgE class switch recombination is regulated by CaMKII via NF-κB alternative pathway
IgE class switch recombination (CSR) is under the tight control to maintain the low concentration of serum IgE. IL-4 and CD40 signal induces IgE CSR. NF-κB classical pathway and STAT6 was indicated in this pathway. In this study, we prepared a M12 cell line expressing TRAF3 in an inducible manner. This cell line showed impaired signal transduction of NF-κB alternative pathway and diminished exp...
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ژورنال
عنوان ژورنال: Integrative Molecular Medicine
سال: 2016
ISSN: 2056-6360
DOI: 10.15761/imm.1000257